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Pilots and Malaria

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Old 24th Mar 2006, 14:17
  #41 (permalink)  
 
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Contract sickle cell anaemia. Parasites can't develop in those who have the condition.
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Old 25th Mar 2006, 09:03
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Grrr

Menikos,
Unfortunately Plasmodium falciparum is constantly evolving and developing resistance to many of the older anti-malarial drugs, especially Chloroquine.
Most of Africa and certainly nearly all tropical countries in Africa, with the exception of Botwswana, Mauritania and Namibia have chloroquine (trade name Paludrine in UK) resistant malaria and taking Paludrine will give very little protection. Paludrine, anyway must always be taken with a weekly dose of Nivaquine. Side effects of these two drugs are stomach irritation, nausea and mouth ulcers. If you are going to an area where you can take Chloroqine (Nivaquine or Avloclor) and Proguanil (Paludrine), the recommended regime is to start taking one week before travelling and continue for 4 weeks after returning. If you are travelling to any of the tropical countries in Africa, the WHO and most tropical medical centres now recommend either one Malarone tablet daily (starting 2 days before you travel and continuing for one week after you return) or one 100mg capsule of Doxycycline daily ((starting 2 days before you travel and continuing for 4 weeks after you return).
Check up on a regular basis what the recommended regime is for the country you're visiting as new drugs are being developed all the time as resistance to old ones is built up. If you're a pilot definitely avoid Mefloquine (Larium) as it can cause depression, anxiety and paranoia in a some people. Definitely stay away from Halofantrine (Halofan) as it has been known to cause irregular heartbeats, even resulting in death.
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Old 25th Mar 2006, 21:41
  #43 (permalink)  

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Tokunbo,

your post and Mr. Twotter´s one about sickle cell aneamia are the only ones here that cover everything (almost) fine and in a correct way.

Obviously a typing error though:
chloroquine (trade name Paludrine in UK)
You must have meant Proguanil there instead of chloroquine. Chloroquine is traded as Nivaquine, Resochin etc.

Quite correct: Paludrine alone does NOT help. You MUST combine Paludrine with chloroquine.

Just for the record, some people get bad skin reactions when exposed to sunshine, under Doxycycline medication. Not a good idea in the tropics...

And then, of course, there is always Gin adn Tonic. You only need about 50 to 80 G&Ts per day to get the appropriate dose of alcohol and quinine.
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Old 26th Mar 2006, 17:21
  #44 (permalink)  
 
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EDDN,
Sorry must have been having a bad day drinking enough Gin and Tonics to keep up my quinine levels
You're quite correct, Chloroquine is normally traded as Avloclor or Nivaquine, and Proguanil hydrochloride normally trades as Paludrine.
The point I was actually trying to make is that they are only effective together and normally only any use against Plasmodium vivax, ovale and malariae. It has little use in most African countries against P. falciparum. As soggyboxers said, currently the best chemoprophylactics are either Malarone or doxycycline, one causing gastro-intestinal irritation and the other photosensitivity. You take your choice
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Old 27th Mar 2006, 10:59
  #45 (permalink)  

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These days, (mainly travelling in and out of West and Central Africa) I tend to use Doxycycline. I was on paludrine/chorloquine for twelve years living in the bush in Ivory Coast: it didn't keep me completely free of malaria but living where we did and doing the job we did being free of malaria was always going to be difficult. My wife had a dreadful time for about eight years and its only when she switched to doxcycline that things really settled down for her. The chloroquine/paludrine thing never worked for her (and larium was worse).

It is well worth noting that if you are in a malaria area and you do get bitten, then malaria becomes a stress related disease. If you get really tired or stressed, then your prophylaxis will really struggle to deal with the parasites. If you are likely to be seriously exposed to palu, take a treatment with you everywhere you go (our family carry arsumax - even though we are mainly based in the UK now).
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Old 27th Mar 2006, 17:20
  #46 (permalink)  
 
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Blah Blah Fishpaste,
Airforce1, do the research before knocking the info
I had done the research...now back yourself up! Tell me that mossies zone in to the Carbon dioxide in your breath.... I need a chuckle
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Old 31st May 2006, 10:20
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Mosquito & Malaria Control

Guys I need some info.

Do people spray Mosquito’s with Aircraft to prevent the spread of Malaria? It’s just a funny for me as it’s the largest single killer in Africa and spraying them from the air would seem an effective method

Any one knows any operators that do this / did this???

Let me know
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Old 31st May 2006, 11:10
  #48 (permalink)  
 
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Malaria does not get sprayed. They treat waterways and lakes, ponds with chemicals to kill of the mosquitos in lavae and pupae stadges - but even that is very controversial... so: I don't think so mate.
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Old 31st May 2006, 13:25
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The treehuggers put up a major fuss way back when it was done by air! Claimed the DDT that was sprayed caused deformities in embryo's etc. Company that has done Tse Tse contracts recently and also had an effect on mozzies, is Orsmond Aerial Spray based in Bethlehem. Did the spraying at night at treetop level!! Large cojones!!!!
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Old 1st Jun 2006, 09:03
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Busy with that right now in Namibia and Botswana.
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Old 2nd Jun 2006, 03:35
  #51 (permalink)  
 
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Helicopter company using a Hughes 500 sprayed for mossie in west africa, will get you the contract name
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Old 2nd Jun 2006, 13:31
  #52 (permalink)  
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Helijet
That used to be Evergreen. Had a friend put one of their 500s in the water there. They sprayed for Black Flys.
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Old 3rd Jun 2006, 11:17
  #53 (permalink)  
 
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Past practices

Years ago in the Okavango, a well-known South African company
used AC500's to night-spray against Tsetse-flies.
Low-level with powerful lights.

Huge outcry from Greenies & Tree-huggers.

By reducing Tsetse, cattle farmers around the Okavango profited.

In the fifties, S-51 helicopters sprayed Northern KZN with DDT & reputedly stocks of that era still remain today. Certain people think it should be re-applied again.
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Old 4th Jun 2006, 10:08
  #54 (permalink)  
 
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There are soft options around now that can be applied without upsetting too many people.

" A - Bait" springs to mind.

It is applied to the water, not a target on the wing, therefore large, less drift prone droplets. In daylight.

It affects only mosquito larvae, preventing proper developement of their wings. Meaning they cannot leave the water.

So, the food chain is relatively unaffected, as fish are still able to feed on them.

Weapon of choice in Queensland, Australia. Not known for malaria but other remarkably similar diseases exist here.
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Old 4th Jun 2006, 14:51
  #55 (permalink)  
 
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I'll bet it's not free, and if it's not given, it aint gonna get used in Africa.

Here our government pollicy is that a good diet should keep most ills away.
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Old 5th Jun 2006, 10:30
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I hear what you are saying.

Got tangled up in the tendering process for some of this work a couple of years back.

The local govt. official in charge of such things let slip that the vehicles "fogging" insecticide in the built up areas here were only sometimes actually loaded with insecticide.

All a matter of public perception, apparantly.
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Old 12th Apr 2007, 14:12
  #57 (permalink)  
 
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Medical

Hi
is any one able to give me infos about the medical aspect of working in countries like Burghina Faso, Mali or Ivory Coast...specifically about the malaria prophylaxis ?
Thanks...
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Old 13th Apr 2007, 04:08
  #58 (permalink)  
 
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Danger

Malaria...DANGEROUS! We all know that but as a Tropical Meds person said to me when I had it you have to know what it is before you treat it! Duh you say!
Fact was felt like flu on Sunday, not so bad Monday, stuffed Tuesday. Blood test negative, Wednesday blood test negative, Thursday blood test negative, Liver function test satisfactory. By the end of Thursday not feeling too good (lack of food etc) Friday Blood test Positive.
Thank god was all I could say, had my Halfan but took about 6 months before I would say all was normal. The moral of this is, the Doc would not give me ANYTHING until he was sure as there are different strains and you can mask one type inadvertantly and make things worse. Pilots by trade are all good self fixers but in this case would say as others did that prevention is by far the better cure!
Sorry if I have duplicated anyone else, 35 years here and only 1 go touch wood!
Fly safe all and sundown to sunrise IS the time for both types of night fighters
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Old 13th Apr 2007, 05:33
  #59 (permalink)  
 
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salvpir,

In all the countries you mention, falciparum malaria is the prevalent strain. It has little use in most African countries against P. falciparum. As previously mentioned on this thread, currently the best chemoprophylactics are either Malarone or doxycycline, one causing gastro-intestinal irritation and the other photosensitivity. Many companies here now issue their expatriate staff with Coartem tablets to take if they think they have malaria while they're out on leave, becasue many doctors in countries which don't have malaria fail to diagnose it, which has led to several people I know dying of it when at home. Definitely stay away from Halofantrine (Halofan) as it has been known to cause irregular heartbeats, even resulting in death. I guess Ratcatcher was lucky when he took his
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Old 13th Apr 2007, 06:08
  #60 (permalink)  
 
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Vibramycin and Orodar.

I recently returned to Kenya coast after many years away . I spent many years in both Kenya and Malawi as a boy pilot and had a few brushes with malaria along the way. Not had it for 20 years now , but understandably was more than a little anxious on my return.
The only anti -malaria dawa /muti / medicine I could get here in the Eastern Med was VIBRAMYCIN from Pfizer , another name for doxycycline . After I paid for it , instructions in GREEK ! , advised to stay out of the sun ! This rather negated the winter holiday / watersports regime planned .
On arrival , I decided to take the path recommended by the locals who live there , and keep the mozzies off . So , nets , spraying , etc etc , but still got nailed by one persistent little buzzer.
Visited the local chemist , same Asian geezer been there 32 years , gave me a course of Coartem in case of malarial attack as well as another little bomb called ORODAR to take concurrently. These are made in Nairobi by Elys Chemical Industries and consist of 500 mg SULFADOXINE and 25 mg PYRIMETHAMINE . I would appreciate anyones experience / opinions on these please. I may go back for longer periods and wouldlike a 'plan'.
I did not use them as I did not contract anything nasty.
By the way , go easy on the G&Ts , malaria loves to attack a weakened liver.
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