The largest aircraft in use are Beech 1900's and HS748's. Prying either of those in and out of those strips takes some real practice, and is likely more dangerous than any risks associated with single engine flying.
I don't think anyone would argue that a Caravan is much more suited to service this location than any twin engine aircraft. The issue here (as far as I'm concerned) is single engine "IFR operations."
To this day, I refuse to get on a single engine commercial flight that will be done in other than VMC.
In poor weather, Summer Beaver can wait.....