SOP's do cater for 'events', though not all. When we have a non-normal in the aircraft, we use SOP's. In an incomprehensible and unknown situation we use our judgement based on various factors (knowledge, skills and experience, among others) to arrive at the safest result. I am sure ATC does the same.
I am interested in ATC's 'Cheklist' or SOP for an RTO, which is a Non-Normal situation