What flynomore has explained is basically what I witnessed some years ago when I was jumseating around with similar cargo outfits. I do not expect the situation to have changed much , possibly even deteriorated due economic situation in some places , looking at Venezuela today.
Somethinge esle : aterpster : thanks for the map. I did not realize that the border with Venezuela was co close to the airport. That could ( emphases " could") perhaps explain why runway 24 was used even with tailwind, to avoid overflying Venezuela, (flight plan , possibly route charges, etc..) It was a domestic flight . I've seen this done in other places.