I would have said EN480B every time but it's not good for four pax (can do in theory but not really good enough).
Same problem for MD500. Plus neither of the above have much baggage space.
That leaves R66, B206 and EC120.
AS350 is overkill and a lot more expensive to own.
Of R66, B206 and EC120 the latter would be by far the most comfortable especially for the passengers. Not much room for the centre passenger in the other two.
But if you want an easy life with lower costs and straight forward maintenance and parts then R66 or B206. The latter has the best safety record.