Maybe we shouldn't blame the crew, until we know what happened and probably not even then.
Night freight pilots tend not to amass hours as quickly as the rest of us, but they had five and eight years experience with the company presumably flying in the area.
It would seem that something catastrophic happened at High altitude and resulted in a near vertical impact. Quite likely a crew with twenty thousand hours each could have done nothing about it either.
RIP guys, and condolences to family and friends.