If you are considering the ME and Emirates (obviously the fact that we are talking about it) you could also apply with Qatar, Etihad and FlyDubai as well.....don't want to start a new debate, just saying they're all in need of pilots.
Also, think about where you would go if you did work for a couple years and left? I don't see many US or Canadian airlines hiring foreign wide body fleet FO's and i definitely would choose the ME over Asia personally.