INeedTheFull90, you can add BRU to your hubs list and SBWKCB, you can add BRU to your limited hubs list. NCL's hubs can be broken down into categories:
LHR, AMS, CDG, they serve everything, short, medium and long haul, North, South, East and West.
DXB, short, medium and Long haul, predominantly South and East except the near east/Iran/Ethiopia/Uganda etc. you get the gist and
EWR which will serve predominantly South and West, except maybe Bermuda?
DUB, transatlantic only
CPH, BRU, limited, very very limited, although connections are available. I may be wrong but I'd assume that BRU could, or should be quite good for African connections.
DUS utterly useless
This is a very crude map but it shows how IST/DXB could coexist,
Great Circle Mapper it shows the destinations available and the direction traveled within 1000nm of each. Although it wouldn't bother me so much, some people won't book to travel back on themselves, i.e NCL-DXB-AMM and would as such prefer NCL-IST-AMM, for example.