Depends upon the time of day you'll be going to work. Currently, traffic on the Sunbury-Bulla-Tullamarine road is woeful during the morning, from 0700-0900. What used to be a 25 minute drive to work, Riddells Creek to Essendon, can take anywhere from 45 minutes to an hour. Romsey, Lancefield, DG, etc all route in this way (unless you take the Wildwood Road back way). Out of morning rush hour, the trip will take 20 minutes to Tulla from Riddell.
Gisborne is quite popular, with the duplication of the Calder the trip to Tulla takes about 20 minutes, although still subject to morning traffic snarls.
All times quoted at the speed limit, of course