Madrid might have 4 strips however the reality is only 3 can simultaneously and safely be used .
If in Northerly Config You Have simultaneous arrivals on 32L and 32R and simultaneous departures on 36L and 36R
That's 4 runways in use.
If Southerly you get simultaneous landings on 18L and 18R and simultaneous take offs on 14L and 14R
(4 Runways)
Never known anything take off on 32L/R unless 36L/R are closed.
SW