I think it's a given we aren't refering to incompetent pilots in this thread. I agree no amount of experience will make up for outright incompetence.
But an inexperienced pilot does not equal an experienced pilot basic aptitude considered roughly equal. It does not even come close, and while it may work out ok on the typical day to day operation - when weather, fuel, ATC, technical or other issues arise I think you would see where experience becomes irreplaceable in a hurry.