Yes an no
For me it was a no brainer after 1 hour on the SEP CPL.
You have just spent 55 hours flying a twin on the IR.
Most of the exercises are the same as the IR but without the screens up.
And the go-around with engine failure you have been doing under screens and visually is a load easier.
And in the twin you just fly every where with a ground speed of 120 knots which makes nav easy.
Now if you go back onto the SEP you have to get back into Single engine work with PFL's glide approaches, EFATO etc. Which do rely a bit on luck on the day that you get it right and mother nature doesn't throw you a wild card.
where as the twin is a lot more fly it on the numbers and it will work.
It doesn't effect your license what you do it in ie if you do it in the twin that doesn't limit you to only flying commercially in a twin.