Cleared to Destination" is a carry over from Ye Goode Olde Dayes when each unit would issue a clearance as you entered their airspace (mainly because radar was not available and they wanted to know where you should be after you'd crashed)/This devolved into, "Cleared Destination, Flight Plan Route'" which earned generations of controllers a thick ear.
Not knowing the ins and outs of a distant approach unit I would issue "Cleared direct destination" as an instructin to set course direct there. If you know the Runway in use and the IP no problems. In the \\UAS several hundred miles from there it's no big thing. I'd expect the instruction to be refined as you got closer.