can't open a page

[Milo Minderbinder]

You need to get your sysadmins on this, not try to do it yourself

However a few guesses as what may have happened

1) in the Internet Explorer Advanced settings, "do not save encrypted pages to disk" has been ticked
2) a security change has blocked javascript
3) a security change has blocked cross-domain posting

A security update could have caused this, someone changing a system policy, new software...... the list goes on
But the fact its happened to more than one machine shows its a system failure and you really need to get a professional to look at it. If you start messing yourself you could end unable disabling your AV software, or punching holes in the firewall

Or have you considered that Sage's systems may have gone tits-up? They had server problems a few days ago. CALL THEM