...it's pretty much impossible to say if the aircraft will fly or not until you reach VR...
Have you thought of;
1) multiple engines stalling or failing
2) reverser deployment (severity varies by type of reverser)
3) structural failure
4) gear collapse (goes with 3)
There are a slew of unlikely scenarios (which have, nonetheless, happened) which would cause me (and caused those involved) to prefer running off the end rather than going in the air.