"I've read all I can read on the Colgan crash. It wasn't fatigue, in my humble opinion. It was pulling instead of pushing, retracting flaps instead of firewall power. It was a lack of flying talent. Sorry to say."
I have to agree with you on the pilot skills in that accident but I'll throw in inexperience as a factor too (for the co-pilot).
However fatigue was also an underlying factor in that accident so says the FAA now. Perhaps if the two pilots (or even only one) had gotten a good night's sleep, maybe just maybe they would have reacted differently to the situation prior to the crash.