The jungle drums are reporting that LHR-MRU is being trundled round the M25 to be a LGW route from November.
But ask yourself the question, why can't they make money flying out of UK regional airports when plenty of others (KL, AF, LH, SK, BE, LS, FR, EZY, ZB, CO, EK, AA, DL, US, QR, EY, AY) so obviously can?
KL, AF, LH, CO, EK,AA, DL,US,QR,EY and even AY feed their hubs from the spoke at the UK regional end into AMS, CDG, FRA/MUC/DUS, DXB, JFK/ORD.ATL/JFK, PHL,DOH, AUH and HEL respectively.
Even BA do exactly the same to LHR from ABZ/EDI/GLA/NCL/MAN feeding long haul and short haul connections.
However exclusive point to point from the UK is something none of the above airlines do, execpet perhaps LH. Point to polint is the market of EZY, LS and FR. For a legacy scheduled carrier to make the numbers add up they need to have interlining traffic and connections over a hub in addition to the point to point traffic.
They are two different business models, one is interconnecting offering connectrions, the othee exclusive point to point. We might one day see UK regional on BA to MAD but only to feed Iberia.
There are a few exceptions with LH but often these are not operated by mainline, but by a franchise or subsidiary.