" Some years ago BA were forced to stop flying the 747 combi as the UKCAA insisted that if the cargo was mixed with pax on the main deck then a fireman (not a pretend fireman) was positioned on the pax side of the bulkhead in full fire gear for the duration of the flight. Now that's safety-and the airline decided double quick time that it wasn't worth the hassle."
What good would the fireman have done on the pax side of the bulkhead?
I remember JAL and ANA were flying combis FRA - NRT. Not sure if the 777 curently used are combis.