Disclaimer: The following is based on anecdotal information and may not be the same experience of others.
The twin hours probably wont help you getting that first job but they certainly do help you cross into the twin work. Most of the guys you'll be up against will only have 182 time anyway. Can I suggest doing it in a useful twin though, consider a Travel air. It has 6 seats and flies like a bonanza, it handles more like a big single than a 182 or a seminole does. Plus it covers you for a be55 which is the most likely twin to be your first.