Joe, I think the question that Callyoushortly was asking, related to whether an A330 was able to physically take-off from EDI; and was not about how many pax were on it.
Anyway, I don't imagine there being a problem since Air Transat operated the same equipment through GLA last summer, and the runway there is only around 300ft longer.
The only problem that may crop up is the fact that there are no parallel taxiways, and this aircraft requires a turning circle of 50m+ (approx).