It'll probably hurt Airbus in the short term. As the recession bites airlines will cancel or delay new aircraft.
However, long term Airbus will undoubtably win. As the recession lifts more and more people will want to fly and airlines will want to fly them by the cheapest method possible. As fleets get older then airlines will have to replace them with something or other.
In many situations this'll be the A380.
10 years from now we'll all be hailing the A380 as one of the major financial successes of the airline industry!