Would a regular BA / VS / a.n.other 74 skipper be able to do the job
If you are hoping that someone with an AF1 jacket will pop into the Three Magpies one night and say "our pilot is tired, does anyone knows how to drive a 742 and hasn't had too many drinks?" I think you will be disappointed. This is a seriously big operation. They normally fly both aircraft (one for the POTUS, one spare) and on long haul routes they must have two crews each. Add to that the extra crews they need for leave, illness, training, medicals and so on and it is clear they must have dozens of people on the roster and can reposition extra crew very easily (the USAF has an awful lot of airplanes).