The A380 doesn't lend itself to a nose door. Double decker loading is impractical. The 747 is fortunate it converts superbly to a freighter, but it will not last forever.
Looking at the 747-8, I cannot see LH, the only pax customer, proceeding. Where does it leave the program- a cargo only aeroplane? At a time when air cargo has collapsed? The program is heading towards a freeze, followed by cancelation. LH will probably order 777-300 to replace the 747-8. Order will be restored!