I think unit costs of the CRJ and Emb 135 / 145's have become unfeasible. So maybe there is a market for something really smashing unit prices..
Probably a next gen prop (fuel efficient) significantly lighter / smaller then the Bombardier Dash series and ATR's. On longer flights airlines will probably rather cut frequencies / fly bigger aircraft ..
Boeing / Airbus see a market for 2000-3000 in the next 20 yrs.