I have seen a small airline 'run' by 3 pretty girls in their 20s (on a Friday afternoon!). It all ticks over. A couple of people in the Ops/Crewing office do all hotel bookings, clearances, permissions, authorisations, rostering, scheduling etc. When you are professional and know your job......I'm not saying they say it at all, but they might agree it all actually runs better like that!
Even a VLA (very large airline) is run by the most junior staff at weekends!