If you're flying WTP then you have a few options.
On some of the 744's, they have the front of the cabin on an emergency exit row. Where this is the case. the outward sides have single seats next to the exits. If you're travelling on your own, choose this seat. Or the seat behind next to the window - you get a bit more legroom and an easy way out!
Otherwise I'd say go for the bulkhead row at the front of WTP. Yes there may be families, however best legroom in class.