It's not that it's a verboten subject but that it's been done to death before.
There MAY be some general differences between men and women but they are just that; general. Some women have more testosterone than others and some men have more oestrogen than others. Whilst their sexuality is not in question, the way in which they think may not follow the "conventions".
Therefore, if you treat everyone as an individual with their own quirks and personality, you'll get along just fine.
Cheers
Whirls