I did the trip 2 years ago from San Diego to Grand Bahamas and back again.
Some places to visit along the route;
New Orleans, I didn't get to New Orleans but I've been told its a nice place to go, especially Mardi Gras
Austin , Texas - Nice city
Tuscon, Az - The aircraft grave yard is worth a visit.
Vegas and the Grand Canyon - Would be high on my list of places to visit if I was you.
All along the Gulf coast and down to the keys in Fl.
As others have said, use airnav.com to assist planning and importantly................ have a good one