From the bit I know, the TSR2 was a magnificent machine. Only the bloated management and the government-directed 'rationalization' of the industry doomed it to failure.
The CF-105 was a worldbeater for its day. Canada did an AMAZING job building an industry practically from scratch. First, the very creditable CF-100, then the Arrow. I believe our side couldn't compete with it so they caused our government to lean heavily on the Canadian government to kill it. Pity.
Of course, all the talent that fled south over the border after the cancellation was a great help in us getting to the moon!