Unless they change their policies, there will always be a market airlines that fly to airports where the runway can't handle and A319/B737-800.
They also don't provide for passengers who want to interline onto inter-continental flights. Although, interlining has become less important as more direct destinations have opened up, I don't think I'd be sticking my neck out if I said that I doubt routes like Newcastle-Maputo or Aberdeen-Buenos Aires will never be provided as a direct flight.