There are some great pics around of an HS 125 somewhere in Africa that waas Fox 2'd by a Mig 21. Took the right engine clean off, a bit of schrapnel (sp?) to the right flap and a hydraulic leak but quite containable. Not saying ASRAAM would be so clean (its got a far better fuse and warhead). However, a single IR missile is unlikely to down an airliner.
On 6 August 1988, the Botswana Air Wing British Aerospace 125-800, flown by Col. Albert Scheffers (CO Botswana Air Wing) and British Aerospace transport pilot Arthur J. Ricketts, carrying the president of Botswana, J. K. Quett Masire and eight other passengers, was underway at 35.000ft over Angola. All of a sudden, those on board heard a loud bang and there was an explosive decompression of the cabin. The aircraft yawed, rolled and dived almost at once and then a shower of fan blades from the starboard Garrett TFF.731-5 engine was observed as it separated away from the aircraft and went in forward direction. The aircraft was hit by one of two R-60/AA-8 Aphid missiles fired at it from an Angolan MiG-23ML interceptor. The first missile hit the starboard engine and ripped it together with the entire pod off the aircraft. The second missile then hit the same engine after it was already off the aircraft. Col. Scheffers regained control of the aircraft at 28.500ft, completed an emergency shutdown and thus preserved the other aircraft systems. 2.000lb of fuel in the right wing and one engine were lost, and there was extensive damage to the right wing and flaps. The aircraft spiraled down and then landed at Cuito Bie, in Angola. Subsequent inspection reveald that the hydraulic pump, starter/generator and alternator were still attached by hoses and cable looms. Angola apologized to Botswana for the missile firing, especially as usual air traffic control clearances had been received before the presidential trip. Nobody on board the aircraft suffered serious injuries, and the aircraft was subsequently repaired. (Photo via Tom N.)