Yes many is the tailwind take off I have flown off RW 21 in B737-200 and -300. The nice thing is that our B737-200 were certified for up to 15 kt tailwind whereas the -300 was 10kt tailwind max so the -200 had a greater degree of flexibility in this area.
Then they promulgated an Emergency Turn off RW 03:-
"At 100 ft (Yes thats ONE HUNDRED FEET) turn right heading 120 degrees...." - all this on ONE engine - GOOD GAME, GOOD GAME!