Generally it is possible to commute from MXP, you should always get 3 days off in a row, it depends a bit on the mood of the scheduler, you might get 5 or even 6 days off every now and then, or then again just 3. Using the jumpseat on the weekend is very very limited, as there are not many flights, so you might need to consider that.
Thanks for all the infos, this is great.
Hard decision to make for me, I have 8 days off in a row at my current job but DHL is a great way to get into long haul territory