I'm a complete novice, but presumably this is an example of an unstable design that require totally on computers and redundant aerodynamic controls to keep it in the sky. Given the reliability of computers and modern engineering this should be very safe once perfected but we all know that software can take time to perfect. The Max shows what happens when something goes wrong but as we are talking about a completed new design certification levels will be much higher. The question is what happens in extreme conditions. Can pilots fly it in direct law? Might airlines want to operate as an all freighter for a few months whilst passengers (and some crews) gain confidence?
Excluding concorde it must be the most radical design since the jet age started.