Unfortunately, we don't know the background to the flight in terms of pilot duty time, rest periods etc.
Bear in mind that a SAR or HEMS pilot faced with a 2 am departure will normally have been on duty for a while but should be adequately rested and, more importantly, mentally prepared to go flying in the middle of the night.
As competent as the 2 pilots may have been, if they had not been expecting to fly they would certainly not have been mentally prepared and their activities before the 'call-out' are presently unknown.
A bunch of rich kids getting plastered during spring break is hardly unusual but alcohol poisoning (if that is what it was) smacks of poor parental supervision.
If panic regarding the girls condition prompted the pilots to be dragged out of bed unexpectedly and asked/ordered to fly then the sense of urgency may well have affected their judgement and risk appreciation.
I cannot stress enough how that 2 am job, even when you are prepared for it, is the time to stop, take a deep breath and do some proper planning and preparation before launching.
I hope, for the sake of the pilots reputation and those who have lost loved ones, that it turns out to be a major malfunction rather than CFIT.
Either way it was a tragic loss of young lives.