From my airline I suspect that a good 40-50% of Captains (bear in mind that’s minimum-the ones that show the obvious signs) would not want to be anywhere near the pointy end of a commercial aircraft with all that responsibility with no First Officer to back them up. The job will totally change and I would suspect that far less pilots are going to want to do the job single handed than the jobs that are saved by single pilot operations. A manning crisis would still result. Not only that but how are you going to train captains of the future in this brave new world?