Personally, I would prefer to see an outright ban on the consumption of any alcohol or medication except for very minor ailments, not less than 48 hours before flight.
Interestingly, perhaps thought should be given to introducing carefully designed, short simulator sessions that could reveal functional and mental shortcomings immediately before every flight. They need not be longer than 10 minutes or so, and if failed, require either a follow up blood test or a programme of retraining. I am aware that this could introduce some serious delay if actioned but the alternative of letting someone loose while incapacitated is unthinkable.
There would, as always, be a cost to be carried, but the airlines could well benefit from an increased level of passenger confidence.