The benefit of having the aircraft based in PMI and operating reverse rotations would be that the airport is quieter during these periods - however, with easyJet, Ryanair, Norwegian and Eurowings already doing the same thing now, the benefit has been already eroded quite significantly. With the demise of Air Berlin, the PMI 'peak' periods are already quieter than they were.
I tend to agree with you Canberra, I like to make the most of my time in a destination if I'm only there for a few days. However, if it's a week in the sun, for me the holiday ends as soon as you lose access to a shower. So I'd rather check out and go home.
If you're not a fan of 3-4am departures, don't move any further East. In Eastern Europe and Russia, holiday flights operate around the clock. 1-2am departures to Egypt and Turkey are the norm.