Surprising how often this comes up. We learn to fly in the left seat, left hand on yoke, right on throttle. We may be lucky enough to fly gliders or some other aircraft with a central stick and left sidewall mounted speed lever and/or throttle. We get a job with an airline and become an FO flying in the right seat with right hand on yoke and left hand on thrust levers. Later on we move to the left seat and are back to left hand on yoke and right hand on thrust levers. I've never found the handedness to be a problem. Generally the transition to a new type or seat involves a whole heap of stuff to learn that far outweighs any minor issues with what hand is doing what.