To be pedantic and not condone any dubious practices, but....
Many on here say it is illegal, not a good idea, etc. to take off overweight. What they really mean it is not a good idea etc. to take off with a load sheet showing you are overweight.
The two are not the same. If you can alter the load sheet, sensibly, you can solve the latter scenario. If you want to ensure the former you'd better be prepared to cancel your slot time, expect to use discretion after having checked all the pax & bag actual weights, incur the wrath of CP for all of the above. Anyone who takes off at load sheet'd MRTOW is taking a blind but legal leap of faith.