So the AFM should also tell the MTOW in case of one engine out during the takeoff phase.
The AFM provides the tools to do the sums, providing that all relevant external data (wx, runway details, obstacles, etc) are input. The resulting, lowest weight becomes the relevant RTOW for the day.
Obviously not something to be attempted on a regular basis but rather something nice to know, "for science" and curiosity.
A routine and trained for exercise on four-engined machines. Only for interest in the sim, otherwise ... prototype Aero Commanders (May 1951) notwithstanding.