There is a full discussion here:
Accident: Emirates A388 over Arabic Sea on Jan 7th 2017, wake turbulence sends business jet in uncontrolled descent
"The Aviation Herald received information that Air Traffic Control all around the globe have recently been instructed to exercise particular care with A380s crossing above other aircraft."
This may be insufficient for safety as it is not really clear how persistent the wake from a 380 actually is. It probably slowly descends and expands. However, for safety it may be necessary for ATC to explicitly apply extra vertical and or lateral separation from the A380's
wake with the A380 making the altitude or heading change as it is the reason for the problem. With Free Route Airspace becoming more common the problem may reduce.