Rhino power,
Though your questions (qouted below) are too general (and the general answer to the first one is "No", IMHO) they are quite wise and touch lots of issues.
IF the F-35 provides the edge over current IADS that it is supposed to do, that's undoubtedly a great operational asset but, given how late into service it is, will it still provide that edge over updated and in development systems? Will the updating of the onboard sensors/avionics be enough to counter the ever evolving IADS threat, or will the basic airframe and LO technologies built into it be the ultimate limiting factor?
IMHO, the key words in the above quote are "current IADS" and "evolving IADS".
As for "current IADS", they differ greatly. For really modern ones, F-35 can hardly do anything alone. But if we add the whole crowd of EW, C4ISR and other platforms, then the question arises about the contribution of F-35 to this orchestra (and its added value vs e.g. the -18's family).
Regarding "evolving IADS", IMHO, as usual the advantage is on the ground systems side (as they are not limited that much in size, power, network links, etc.) Therefore, taking into account very long life cycles of modern planes (as compared e.g. with 50's and 60's) "modifiability" (quick and cost effective) becomes more and more important for any aircraft.