Una Due Tfc.
I'm not sure I understand the "inconvenience and wasted time of getting to PWK" bit.
I have been doing rotation work overseas for almost twenty years and don't have allegiance to any airport.
The only thing I look at when planning my route is which one allows me more time at home. At present I go from EDI to CDG as I can get an extra night at home on the outward leg. Coming back, I come via EDI on the mid morning direct flight. This flight will not be running in April so I will route via AMS to GLA. If there was an alternative via Prestwick I would be weighing that up as well.
A colleague who lives in Ayrshire gets driven to EDI on his outbound leg for the same reason as I do.
I've been sailing in the Firth of Clyde in the afternoon before my journey, wondering why some people have already begun their journeys from their local airports to do overnight stays in AMS or Paris.