Interesting question. The taxiway markings at a runway/taxiway intersection are considered mainly for lead-off purposes so ensuring a vacating aircraft following the marking doesn't leave the paved surface. The markings do serve as lead-on guidance for take-off but often once the aircraft goes beyond the holding point onto the runway pilots deviate from the line to reduce the line-up allowance knowing there should be sufficient pavement runway width to do this safely. Airports should bear this in mind when designing blast pads at runway ends to ensure they are secure and can cope with the increased jet blast from this type of manoeuvre.