There should be only a minor difference.However it also depends upon the software of the Computerised LS.Some versions calculate the SLIGHTLY INCREASED nose up trim correction for reduced thrust settings (assumed temp), which can be around 1 unit nose up correction for a fully derated thrust setting.Others dont make this correction leading to a difference in STAB TRIM setting, in this case you should apply the correction yourself, and the only place you can find a reference to this might be a table in the Weight and Balance Manual.Obviously if you use full thrust then no correction might be required.....Peter.