I doubt anything in a cargo hold could survive, and the potential (in my mind) for distribution of the gas through the aircon still fills me with dread.
FWIW Given a percentage of the air you breath is sourced externally ( engine bleed air) and much more importantly given the direction and amount of airflow within the cabin and holds is reconfigured once you arm the cargo fire system (prior to discharge) to cater amongst other things for both possible smoke and the extinguisher discharge recirculation via the aircon
shouldn't be an issue....(it says here in my 777 FCOM)...