A HUD helps a lot, too. I have, for some reason, always come in from the west on the RNAV (GNSS) Y Rwy 02R approach or just off a visual inside Corcavado. It's not quite as tight as it looks, but demands some real hand flying. Time of day may have something to do with direction of landing, I think there is a wind shift that's fairly predictable.
WRT KCRQ, been there many times, a Global can lift 8-10 pax and about 29,000 pounds of fuel, call it 7 hours with plentiful reserves at M.85.
GF