A key issue here will be the level and frequency of tail wind speeds, given the constraints these can place on aircraft performance. We are gathering more data on both wind patterns and speeds to facilitate these considerations.
Good luck with that, at any airport, where the crew need to make a decision based on a 6 hour arrival forecast made 6 hours in advice of decision time. i.e. the forecast is 12 hour old when you arrive in a culdesac low on fuel. I used to do that from Italy to Caribbean: load max full and blast off, but the airport was less dangerous and the altn was closer by. Even then it felt uncomfortable as the return crew was at destination not the alternate. One way or another the a/c needed to be at A not B.