Yes the Boeing 727-200 were scheduled for Transcontinental trip constantly in late 70's and throughout the 80's. From memory SYD - PER if flight has strong headwinds or alternative requirements use to go into Meekatharra and maybe Kalgoorlie in a squeeze when runway there was a lot smaller.
Ansett in about 87/88 bought 3 or 4 Long-Range versions, Boeing 727-200 LR's for Long Range ANA/B/C and F I recall. Think they had a large influence on Boeing to fit more fuel tanks to 727-200.